961. We have 30 ml of a solution that contains 6 grams of the active drug moiety. Calculate the concentration of the drug in mg/ml?
a- 180
b- 200
c- 220
d- 240
e- 260
962. Elixirs containing at least how much percentage of alcohol will achieve the 'self-preserving' character?
a- 3 - 5 %
b- 7 - 8 %
c- 10 - 12 %
d- 33 %
e- 70 %
963. In the Wet Gum Method of emulsion preparation, the oil, water, and gum are used in the ratio of;
a- 1:2:1
b- 2:2:4
c- 3:4:2
d- 4:2:1
e- 4:2:2
964. The chemical nature of the co-enzyme is;
a- mineral
b- vitamin
c- protein
d- carbohydrate
e- lipid
965. A pharmacy technician is going to prepare a solution that contains 6.5% of a drug. The stock solution available of the same drug is 15% w/v. What volume of the stock solution must be taken in order to prepare the required solution?
a- 6.5 mL
b- 15 mL
c- 21.5 mL
d- 42 mL
e- 43.3 mL
966. The aseptic technique is used for:
a- administering parenteral medications
b- performing urinary catheterization
c- extemporaneous preparations
d- ophthalmic preparations
e- all of the above
967. The coordinated interaction between the hypothalamus, anterior pituitary, and adrenal cortex results in the production and delivery of the hormone called 'cortisol'. What is expected after this hormone is released in the body?
a- decreased inflammation
b- decreased protein breakdown
c- increased gluconeogenesis
d- increased insulin release
e- both a and c
968. At position 7 in the molecular structure of Levofloxacin, a piperazine group is present. The role of this group according to the structure-activity relationship (SAR) is;
a- enhances the gram-positive activity
b- decrease the activity of the efflux pump as a mechanism of resistance
c- improves activity against gram-negative bacteria
d- increases the oral absorption of the drug molecule
e- improves both gram-positive and gram-ve activity
969. What is the average shelf life for a reconstituted and refrigerated ampicillin suspension?
a- 3 days
b- 7 days
c- 14 days
d- 28 days
e- 2 months
970. Saponification number gauges the number of fatty acids contained in the fats. This is known by finding the number of milligrams of a certain compound that are used to saponify one gram of fat. That compound is;
a- sodium hydroxide
b- potassium bromide
c- hydrochloric acid
d- potassium hydroxide
e- a or d
971. Which epidemiological study starts with the outcome and looks back in time to exposure?
a- case-control study
b- retrospective cohort study
c- descriptive study
d- cross-sectional study
e- non-randomized controlled study
972. Individuals that are carriers of a genetic variant of a certain cytochrome P450 isoform can experience hyper-responsiveness to small doses of warfarin and thus can result in overdose readily. That certain cytochrome P450 isoform is?
a- CYP2C9
b- CYP2D6
c- CYP3A4
d- CYP2C19
e- CYP1A2
973. Which agent is INCORRECTLY paired with appropriate clinical use of the drug?
a- oxytocin - used to induce labor and milk ejection from breasts
b- insulin degludec - treatment of diabetes insipidus
c- liotrix - treatment of hypothyroidism
d- goserelin - treatment of breast and prostate cancer
e- hCG - treatment of infertility
974. Which of the following antidiabetic drugs can cause weight loss?
a- insulin
b- glimepiride
c- pioglitazone
d- glinides
e- empagliflozin
975. HIT or heparin-induced thrombocytopenia is a severe complication that can develop in patients exposed to any form or amount of heparin products. This complication is characterized by;
i- a high risk for thrombosis
ii- a fall in platelet counts
iii- blood loss in urine
iv- hyperkalemia
v- hypotension
CHOOSE THE CORRECT OPTION?
a- all of the options are correct
b- only options i and ii are correct
c- all of the options except i are correct
d- only options iii and iv and v are correct
e- only option ii is correct
976. Point out the statement that is NOT TRUE?
a- vitamin B3 is also known as nicotinic acid
b- aliskiren is an anti-hypertensive drug
c- cox-2 inhibitors are safe in cardiovascular patients
d- niosomes can deliver both hydrophilic and hydrophobic drugs
e- absorption of famotidine increases if taken with food
977. Consuming expired or degraded tetracyclines can result in Fanconi syndrome. Basically, this syndrome consists of dysfunction of the;
a- proximal renal tubules
b- auditory apparatus
c- optic nerves
d- cerebellum
e- hepatocytes
978. A patient comes to the pharmacy with a prescription for 0.5 milligrams of IM adrenaline. The injection available on the site is 100 micrograms per mL. How many milliliters of this injection should be dispensed to supply the required dose to the patient?
a- 5 mL
b- 15 mL
c- 25 mL
d- 50 mL
e- 100 mL
979. A patient of hypothyroidism is being treated with thyroid supplementation. Which symptom(s) does NOT indicate that this patient may require a higher dosage of levothyroxine?
a- palpitations
b- cold intolerance
c- bradycardia
d- unexplained weight gain
e- all of the above
980. As per pharmacopeial requirements, the temperature of the medium during the disintegration test (DT) of tablets or capsules is kept at;
a- 15°C
b- 25°C
c- 30°C
d- 37°C
e- 100°C
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Answer Keys
MCQ # - Correct option
961- b
962- c
963- d
964- b
965- e
966- e
967- e
968- c
969- c
970- e
971- a
972- a
973- b
974- e
975- b
976- c
977- a
978- a
979- a
980- d
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