- Chlorpheniramine has neither specific antitussive nor expectorant nor bronchodilator action, but is commonly present in proprietary cough formulations.
- Noscapine (an antitussive) is present in opium but has no analgesic or addicting properties.
- Dextropropoxyphene is a codeine like analgesic which has poor antitussive action. Its levo-isomer is antitussive.
- Oxeladin, Clophedianol and Dextromethorphan are anti-tussives used in dry cough treatment.
- Antitussives act by raising the threshold of cough center and reducing cough-inducing impulses from the lungs.
- Mucokinetic is a drug which makes respiratory secretions more watery.
- Codeine is used clinically as an Analgesic, Antitussive and as an Antidiarrhoeal.
- Bromhexine (mucolytic) acts by depolymerizing mucopolysaccharides present in sputum.
- Potassium iodide (an expectorant) acts both directly on the airway mucosa as well as reflexly.
- Bronchodilators are useful in cough only when reflex bronchoconstriction is associated.
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Pharmacy Exam Points (to remember)... Set 25
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