Pharmacy Exam Points (to remember)... Set 8

1. The non-steroidal anti-inflammatory drugs are more effective in migraine that is without aura. 
2. Ergotamine relieves migraine by constricting cranial vessels and reducing perivascular neurogenic inflammation.
3. The most critical risk in the use of sumatriptan for the treatment of migraine is precipitation of coronary vasospasm.
4. Sumatriptan tends to suppress both pain and vomiting in migraine.
5. Propranolol is most commonly used for prophylaxis of migraine.
6. Propranolol, Timolol, and Atenolol are the β-blockers which can be used for prophylaxis in migraine but not Pindolol. 
7. Prophylactic therapy of migraine benefits up to 70pc patients of moderate to severe migraine. 
8. Flunarizine is the calcium-channel blocker that is used for prophylaxis of migraine but not for angina pectoris.
9. Prostaglandins, Leukotrienes, Angiotensin II are the autacoids of which there are no pre-formed stores.
10. The cyclooxygenase isoenzymes COX-1 and COX-2 differ from each other in that COX-1 is constitutive while COX-2 is largely inducible.