Pharmacy Subjects MCQs with Answer Keys - MCQ # 601 to 650 - Part 61

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Drug Law MCQs - MCQ # 601, 606, 620, 622, 624, 627, 629-632

MCQ # 602-605, 607-612

MCQ # 613-619, 621, 623, 625

MCQ # 626, 628, 633-636, 647-650

Medicinal Chemistry MCQs - MCQ # 637 to 646

The same MCQs in TEXT format.

601. The Drug Act 1976 defines the misbranded drug as;

a- label or packing resemble that of another manufacturer's brand

b- does not contain the claimed active ingredient

c- not labelled in the prescribed manner

d- contains foreign matter

e- black market drug

602. The 'eicosa' part of eicosanoids refers to;
a- 6 carbon atoms

b- 10 carbon atoms

c- 20 carbon atoms

d- 30 carbon atoms

e- 46 carbon atoms

603. Which statement of the following is incorrect regarding paracetamol;
a- has no anti-inflammatory effects

b- has no GI side effects as NSAIDs have
c- not safe in cardiovascular patients

d- acts via PG synthesis inhibition

e- its max. daily dose in adults is 4 grams

604.  Identify the NSAID among the following that has no antipyretic activity?

a- flurbiprofen

b- naproxen

c- mefenamic acid

d- diflunisal

e- aspirin

605. Phototherapy that is indicated for the treatment of neonatal jaundice uses the wavelength of;
a- UV light
b- red light
c- yellow light
d- blue light
e- violet light

606. As per Drug Law, to open a distribution setup of medicines, one has to apply through;

a- Form 3

b- Form 6

c- Form 9

d- Form 10

e- Form 11

607. The only irreversible inhibitor of cyclooxygenase among the following is;

a- aspirin

b- paracetamol

c- ibuprofen

d- indomethacin

e- diflunisal

608. Identify the antihistamine among the following that is also an appetite stimulant?

a- fexofenadine

b- ebastine

c- diphenhydramine

d- hydroxyzine

e- cyproheptadine

609.  Antihistamine that can easily cross the blood brain barrier and thus produce sedation is;

a- fexofenadine

b- cetirizine

c- levocetirizine

d- loratadine

e- diphenhydramine

610. The gastrointestinal adverse effects of Orlistat can be minimized through a plan of low-fat diet and concomitant administration of;

a- omeprazole

b- vitamin D

c- cholestyramine

d- dimenhydrinate

e- loperamide

611. Among the below, identify the prophylactic anti-migraine medication?

a- dihydroergotamine

b- naproxen sodium

c- amitriptyline

d- zolmitriptan

e- diclofenac potassium  

 

612. The only anti-obesity preparation among the following that has no adverse effect of suicide ideation is;

a- bupropion+naltrexone

b- liraglutide

c- lorcaserin

d- orlistat

e- no anti-obesity prep. have such adverse effect

613. The most common side effect associated with obesity medication orlistat, that mostly results in patients stop taking this drug, is;

a- severe headache

b- flatulence and increased defecation

c- suicidal ideation

d- severe heartburn

e- palpitations

614. Identify anti-obesity medication among the following that is teratogenic;

a- bupropion+naltrexone

b- phentermine+topiramate

c- liraglutide

d- phentermine

e- diethylpropion

615. The longest acting triptan among the below is;

a- zolmitriptan

b- sumatriptan

c- rizatriptan

d- almotriptan

e- frovatriptan

616, In humans, how many types of blood groups are there in total?

a- 2

b- 3

c- 4

d- 8

e- 10

617. In general the rarest blood group is;
a- O-positive

b- A-negative

c- B-negative

d- B-positive

e- AB-negative

 

618. The term 'metabolic syndrome' indicates;

a- obesity

b- hypertension

c- type 2 diabetes

d- cardiovascular disease

e- its an umbrella term for all of the above

619. Which category of enzymes catalyze the joining of two large molecules by forming a new chemical bond between them?

a- oxidoreductases

b- ligases

c- transferases

d- isomerases

e- hydrolases

620. According to Drug Act 1976, a medicine in the market that does not contain the active ingredient it claims to have is referred to as;

a- misbranded

b- counterfeit

c- spurious

d- adulterated

e- second-hand

621. In general the most common blood group type is;

a- O-positive

b- A-negative

c- B-negative

d- B-positive

e- AB-negative

622. As per Drug Act 1976, the counterfeit drug is;

a- label or packing resemble that of another manufacturer's brand

b- does not contain the claimed active ingredient

c- not labelled in the prescribed manner

d- contains foreign matter

e- black market drug

623. GLP-1 receptor agonists are indicated in;
a- appetite stimulation
b- skeletal muscle stimulation
c- obesity
d- serotonin syndrome
e- extrapyramidal side effects management

624. In Drug Law, Form 9 is for the purpose of;

a- license to sell drugs in a pharmacy

b- license to manufacture drugs

c- license to sell drugs in a distribution setup

d- registration of an imported drug

e- license to sell drugs in a medical store

625. An anti-obesity drug, Orlistat works by reducing fat absorption. It reduces this fat absorption by about;

a- 99 %

b- 80 %

c- 60 %

d- 45 %

e- 30 %

626. A pharmaceutical document that contains all the information about a product including its master formula, all its ingredients along with their roles and percentages in the formulation, clinical trials, manufacturing procedure, quality control tests, detail of manufacturing plant, warehouse capacities and facilities, information related to safety, efficacy, bioavailability and anything crucial is called as;

a- pharmaceutical compendium

b- pharmaceutical literature

c- pharmaceutical index

d- pharmaceutical dossier

e- pharmaceutical user's manual

627. The practical body established to provide for effective coordination and enforcement of the Drug Act 1976 and to bring harmony in interprovincial trade and commerce of therapeutic goods is;

a- PQCB

b- Drugs Appellate Board

c- DRAP

d- CLB
e- PPA

628. NSAID that has the highest COX-1 selectivity is;

a- aspirin

b- flurbiprofen

c- naproxen

d- ketorolac

e- etodolac

629. In Drug Act 1976, the Section 9 denotes;

a- Appellate Board

b- Provincial Quality Control Board

c- Provincial Drug Testing Laboratory

d- Pakistan National Formulary

e- Powers of inspectors

630. As per drug rules, the word MEDICAL STORE should be displayed on medical stores on a;

a- green colored signboard

b- red colored signboard 

c- blue colored signboard

d- yellow colored signboard

e- any colored signboard

631. In Drug Act 1976, the power to fix maximum prices of drugs comes under section;

a- 6

b- 12

c- 18

d- 24

e- 31 

632. According to The Factories Act of 1934, seasonal factories (are);

a- factories that operates through all the seasons

b- tea, coffee, cotton and sugar factories

c- engage in not more than 180 working days

d- remains operational for a 90 days season in a year

e- both b and c are correct

633. UV-Visible Spectrophotometry uses ultraviolet and visible regions of the electromagnetic radiation spectrum. The part of the visible region that has the highest wavelength among the following is;

a- violet region

b- blue region

c- green region

d- yellow region

e- red region

634. Pharmaceutical coating agents plays role in;

a- protection

b- elegance

c- swallow-ease

d- identification

e- all of the above

635. The sweetest sugar among the following is;

a- glucose

b- sucralose

c- sucrose

d- sodium cyclamate

e- fructose

636. In the Sweetness Index of sugars, the reference standard is generally;

a- maltose

b- glucose

c- sucrose

d- fructose

e- lactose 

637. The metabolism of xenobiotics takes place in;

a- liver

b- lungs

c- kidneys

d- nasal epithelium

e- all of the above

638. There is a definite relationship between the structure of a drug molecule and its pharmacological activity. Replacing the aromatic ring in ephedrine with an alkyl group will result in;

a- increased appetite suppression

b- increased decongestion activity

c- decreased CNS stimulation

d- increased vasoconstriction activity

e- loss of all pharmacological activity

639. Identify the anthelmintic drug(s) among the following; 

a- albendazole

b- ivermectin

c- nitazoxanide

d- levamisole

e- all of the above

640. The nephrotoxic anti-TB drug among the below is;

a- isoniazid

b- ethambutol

c- pyrazinamide

d- rifampicin

e- streptomycin

641. Cytochrome P450 enzymes are found in;

a- liver

b- lungs

c- all of the options

d- brain

e- adrenal tissue

642. In medical literature, the shorthand used for anti-TB drug Isoniazid is;

a- INZ

b- IND

c- INH

d- ISZ

e- IZD

643. The antiviral drug Amantadine exerts its action by affecting which step in the viral replication process?

a- absorption

b- uncoating

c- nucleic acid synthesis

d- protein synthesis

e- packing

644. Terramycin is a Pfizer company brand for;

a- tetracycline

b- chlortetracycline

c- oxytetracycline

d- doxycycline

e- demeclocycline

645. Identify the natural penicillin(s) among the following;

a- penicillin G

b- penicillin K

c- penicillin X

d- penicillin F

e- all of the above

646. The molecular structure of Aspirin is; 

  

647. Prostaglandin among the following that is used in the eyes for the treatment of open-angle glaucoma is;

a- alprostadil

b- lubiprostone

c- bimatoprost

d- misoprostol

e- epoprostenol

648. The usual recommended frequency of administration of the immunomodulator drug abatacept in the treatment of autoimmune diseases like rheumatoid arthritis is;

a- once daily

b- twice daily

c- once weekly

d- twice weekly

e- every 4 weeks

649. Which statement correctly represents the mechanism of action of methotrexate?

a- xanthine oxidase inhibitor

b- IL-5 inhibitor

c- janus kinase inhibitor

d- DHFR inhibitor

e- TNF blocker

650. NSAID with highest COX-2 selectivity is;

a- aspirin

b- indomethacin

c- ketorolac

d- etodolac

e- piroxicam

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Answer Keys

MCQ # - Correct option

601- c

602- c

603- c

604- d

605- d

606- e

607- a

608- e

609- e

610- c

611- c

612- d

613- b

614- b

615- e

616- d

617- e

618- e

619- b

620- c

621- a

622- a

623- c

624- a

625- e

626- d

627- c

628- d

629- a

630- c

631- b

632- e

633- e

634- e

635- b

636- c

637- e

638- d

639- e

640- e

641- c

642- c

643- b

644- c

645- e

646- a

647- c

648- e

649- d

650- d