Color Atlas of Pharmacology - 2nd edition - PDF Book

Color Atlas of Pharmacology

2nd edition

Authors

Heinz Lüllmann

Klaus Mohr

Albrecht Ziegler

Detlef Bieger

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CONTENTS OF THIS BOOK

General Pharmacology

History of Pharmacology

Drug Sources

-- Drug and Active Principle

-- Drug Development

Drug Administration

-- Dosage Forms for Oral, and Nasal Applications

-- Dosage Forms for Parenteral Pulmonary

-- Rectal or Vaginal, and Cutaneous Application

-- Drug Administration by Inhalation

-- Dermatologic Agents

-- From Application to Distribution

Cellular Sites of Action

-- Potential Targets of Drug Action

Distribution in the Body

-- External Barriers of the Body

-- Blood-Tissue Barriers

-- Membrane Permeation

-- Possible Modes of Drug Distribution

-- Binding to Plasma Proteins

Drug Elimination

-- The Liver as an Excretory Organ

-- Biotransformation of Drugs

-- Enterohepatic Cycle

-- The Kidney as Excretory Organ

-- Elimination of Lipophilic and Hydrophilic Substances

Pharmacokinetics

-- Drug Concentration in the Body as a Function of Time

-- First-Order (Exponential) Rate Processes

-- Time Course of Drug Concentration in Plasma

-- Time Course of Drug Plasma Levels During Repeated Dosing and During Irregular Intake

-- Accumulation: Dose, Dose Interval, and Plasma Level Fluctuation

-- Change in Elimination Characteristics During Drug Therapy

Quantification of Drug Action

-- Dose-Response Relationship

-- Concentration-Effect Relationship – Effect Curves

-- Concentration-Binding Curves

Drug-Receptor Interaction

-- Types of Binding Forces

-- Agonists-Antagonists

-- Enantioselectivity of Drug Action

-- Receptor Types

-- Mode of Operation of G-Protein-Coupled Receptors

-- Time Course of Plasma Concentration and Effect

Adverse Drug Effects

-- Drug Allergy

-- Drug Toxicity in Pregnancy and Lactation

Drug-independent Effects

-- Placebo – Homeopathy

Systems Pharmacology

-- Drug Acting on the Sympathetic Nervous System

-- Sympathetic Nervous System

-- Structure of the Sympathetic Nervous System

-- Adrenoceptor Subtypes and Catecholamine Actions

-- Structure – Activity Relationship of Sympathomimetics

-- Indirect Sympathomimetics

-- alpha-Sympathomimetics, alpha-Sympatholytics

-- beta-Sympatholytics (beta-Blockers)

-- Types of beta-Blockers

-- Antiadrenergics

Drugs Acting on the Parasympathetic Nervous System

-- Parasympathetic Nervous System

-- Cholinergic Synapse

-- Parasympathomimetics

-- Parasympatholytics

Nicotine

-- Ganglionic Transmission

-- Effects of Nicotine on Body Functions

-- Consequences of Tobacco Smoking

Biogenic Amines

-- Biogenic Amines – Actions and Pharmacological Implications

-- Serotonin

Vasodilators

-- Vasodilators – Overview

-- Organic Nitrates

-- Calcium Antagonists

Inhibitors of the RAA System

Drugs Acting on Smooth Muscle

-- Drugs Used to Influence Smooth Muscle Organs

Cardiac Drugs

-- Overview of Modes of Action

-- Cardiac Glycosides

-- Antiarrhythmic Drugs

-- Electrophysiological Actions of Antiarrhythmics of the Na+-Channel Blocking Type

Antianemics

-- Drugs for the Treatment of Anemias

-- Iron Compounds

Antithrombotics

-- Prophylaxis and Therapy of Thromboses

-- Coumarin Derivatives – Heparin

-- Fibrinolytic Therapy

-- Intra-arterial Thrombus Formation

-- Formation, Activation, and Aggregation of Platelets

-- Inhibitors of Platelet Aggregation

-- Presystemic Effect of Acetylsalicylic Acid

-- Adverse Effects of Antiplatelet Drugs

Plasma Volume Expanders

Drugs used in Hyperlipoproteinemias

-- Lipid-Lowering Agents

Diuretics

-- Diuretics – An Overview

-- NaCI Reabsorption in the Kidney

-- Osmotic Diuretics

-- Diuretics of the Sulfonamide Type

-- Potassium-Sparing Diuretics

-- Antidiuretic Hormone (/ADH) and Derivatives

Drugs for the Treatment of Peptic Ulcers

-- Drugs for Gastric and Duodenal Ulcers

Laxatives

Antidiarrheals

-- Antidiarrheal Agents

Other Gastrointestinal Drugs

Drugs Acting on Motor Systems

-- Drugs Affecting Motor Function

-- Muscle Relaxants

-- Depolarizing Muscle Relaxants

-- Antiparkinsonian Drugs

-- Antiepileptics

Drugs for the Suppression of Pain, Analgesics

-- Pain Mechanisms and Pathways

Antipyretic Analgesics

-- Eicosanoids

Antipyretic Analgesics and Antiinflammatory Drugs

-- Antipyretic Analgesics

Antipyretic Analgesics

-- Nonsteroidal Antiinflammatory (Antirheumatic) Agents

-- Thermoregulation and Antipyretics

Local Anesthetics

Opioids

-- Opioid Analgesics – Morphine Type

General Anesthetic Drugs

-- General Anesthesia and General Anesthetic Drugs

-- Inhalational Anesthetics

-- Injectable Anesthetics

Hypnotics

-- Soporifics, Hypnotics

-- Sleep-Wake Cycle and Hypnotics

Psychopharmacologicals

-- Benzodiazepines

-- Pharmacokinetics of Benzodiazepines

-- Therapy of Manic-Depressive Illness

-- Therapy of Schizophrenia

-- Psychotomimetics (Psychedelics, Hallucinogens)

Hormones

-- Hypothalamic and Hypophyseal Hormones

-- Thyroid Hormone Therapy

-- Hyperthyroidism and Antithyroid Drugs

-- Glucocorticoid Therapy

-- Androgens, Anabolic Steroids, Antiandrogens

-- Follicular Growth and Ovulation, Estrogen and Progestin Production

-- Oral Contraceptives 

-- Insulin Therapy

-- Treatment of Insulin-Dependent Diabetes Mellitus

-- Treatment of Maturity-Onset (Type II) Diabetes Mellitus

-- Drugs for Maintaining Calcium Homeostasis

Antibacterial Drugs

-- Drugs for Treating Bacterial Infections

-- Inhibitors of Cell Wall Synthesis

-- Inhibitors of Tetrahydrofolate Synthesis

-- Inhibitors of DNA Function

-- Inhibitors of Protein Synthesis

-- Drugs for Treating Mycobacterial Infections

Antifungal Drugs

-- Drugs Used in the Treatment of Fungal Infection

Antiviral Drugs

-- Chemotherapy of Viral Infections

-- Drugs for Treatment of AIDS

Disinfectants

-- Disinfectants and Antiseptics

Antiparasitic Agents

-- Drugs for Treating Endo- and Ectoparasitic Infestations

-- Antimalarials

Anticancer Drugs

-- Chemotherapy of Malignant Tumors

Immune Modulators

-- Inhibition of Immune Responses

Antidotes

-- Antidotes and treatment of poisonings

Therapy of Selected Diseases

-- Angina Pectoris

-- Antianginal Drugs

-- Acute Myocardial Infarction

-- Hypertension

-- Hypotension

-- Gout

-- Osteoporosis

-- Rheumatoid Arthritis

-- Migraine

-- Common Cold

-- Allergic Disorders

-- Bronchial Asthma

-- Emesis

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