21. Microbial resistance to Penicillin G is there because of the following;
a. Production of b-lactamases
b. Decreased permeability to the drug
c. Active removal of the drug through efflux pump
d. Altered Penicillin-binding proteins
e. All of the above
22. MRSA resistance to most commercially available β-lactam antibiotics is because of the;
a. Production of b-lactamases
b. Decreased permeability to the drug
c. Active removal of the drug through efflux pump
d. Altered Penicillin-binding proteins
e. All of the above
23. Klebsiella pneumoniae presents resistance to antibiotics through the following mechanism;
a. Production of b-lactamases
b. Decreased permeability to the drug
c. Active removal of drug through efflux pump
d. Altered Penicillin-binding proteins
e. All of the above
24. Pseudomonas aeruginosa presents resistance to antibiotics through the following mechanism;
a. Production of b-lactamases
b. Decreased permeability to the drug
c. Active removal of drug through efflux pump
d. Altered Penicillin-binding proteins
e. All of the above
25. Which one of the following penicillins particularly have the potential to cause acute interstitial nephritis and for that reason no longer used clinically;
a- dicloxacillin
b- carbenicillin
c- methicillin
d- ticarcillin
e- phenbenicillin
26. Which one of the following fluoroquinolones does not need dosage adjustment in case of renal impairment and thus can be given as such in renal dysfunction;
a- ciprofloxacin
b- moxifloxacin
c- delafloxacin
d- ofloxacin
e- gemifloxacin
27. All of the following fluoroquinolones are primarily excreted in urine except;
a- ciprofloxacin
b- levofloxacin
c- norfloxacin
d- moxifloxacin
e- gemifloxacin
28. Which of the following macrolide / ketolide has the longest half-life of all ?
a- erythromycin
b- clarithromycin
c- azithromycin
d- telithromycin
29. The following fluoroquinolone is available as an oral formulation only;
a- gemifloxacin
b- levofloxacin
c- norfloxacin
d- moxifloxacin
e- delafloxacin
30. The following is a first-line therapy for community acquired pneumonia (CAP);
a- gemifloxacin
b- levofloxacin
c- norfloxacin
d- moxifloxacin
e- delafloxacin
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Answer Keys
Answer Keys
MCQ # - Correct option
21- d
22- d
23- c
24- b
25- c
26- b
27- d
28- c
29- a
30- b
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